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구본산

구본산

류마티스내과

전문과목

류마티스관절염, 골관절염, 통풍, 베체트병, 염증성근염, 혈관염, 강직척추염, 전신홍반루푸스, 골다공증, 전신경화증, 섬유근육통

진료시간

월, 화, 수, 목, 금, 토
오전
오후
학력사항

한양대학교 의과대학 졸업

울산의대 대학원 의학석사

울산의대 대학원 의학박사

경력사항

인제대학교 서울백병원 조교수, 부교수

인제대학교 일산백병원 부교수, 교수

도쿄대학교 알레르기/류마티스내과 연수


주요활동

대한류마티스학회 정회원

대한의료정보학회 정회원

논문/저서

1: Koo BS, Park KY, Lee HJ, Kim HJ, Ahn HS, Yim SY, Jun JB. Effect of combined pulmonary fibrosis and emphysema on patients with connective tissue diseases and systemic sclerosis: a systematic review and meta-analysis. Arthritis Res Ther. 2021 Apr 6;23(1):100. doi: 10.1186/s13075-021-02494-y. PMID: 33823923; PMCID: PMC8022385.


2: Nam B, Koo BS, Nam SW, Shin JH, Song Y, Cho SK, Sung YK, Kim TH. Gender differences in factors associated with low quality of life and depression in

Korean patients with ankylosing spondylitis. Qual Life Res. 2021 Mar 10. doi: 10.1007/s11136-021-02800-w. Epub ahead of print. PMID: 33689133.


3: Nam B, Koo BS, Lee TH, Shin JH, Kim JJ, Lee S, Joo KB, Kim TH. Low BASDAI score alone is not a good predictor of anti-tumor necrosis factor treatment

efficacy in ankylosing spondylitis: a retrospective cohort study. BMC Musculoskelet Disord. 2021 Feb 4;22(1):140. doi: 10.1186/s12891-020-03941-8.

PMID: 33541326; PMCID: PMC7860220.


4: Ha SY, Shim YB, Lee MY, Koo BS, Kim JH, Jeon JY, Yoo HJ, Kim YJ, Shin JY, Park MH. Comparative Cost-Effectiveness of Tofacitinib With Continuing

Conventional Synthetic Disease-Modifying Anti-Rheumatic Drugs for Active Rheumatoid Arthritis in South Korea. Rheumatol Ther. 2021 Mar;8(1):395-409. doi: 10.1007/s40744-021-00278-z. Epub 2021 Jan 26. PMID: 33496958; PMCID: PMC7991041.


5: Koo BS, Lim YC, Lee MY, Jeon JY, Yoo HJ, Oh IS, Shin JY, Kim TH. The risk factors and incidence of major infectious diseases in patients with ankylosing

spondylitis receiving tumor necrosis factor inhibitors. Mod Rheumatol. 2021 Feb 15:1-14. doi: 10.1080/14397595.2021.1878985. Epub ahead of print. PMID:

33494621.


6: Koo BS, Lim YC, Lee MY, Jeon JY, Yoo HJ, Oh IS, Shin JY, Kim TH. Dose Reduction of Tumor Necrosis Factor Inhibitor and its Effect on Medical Costs for

Patients with Ankylosing Spondylitis. Rheumatol Ther. 2021 Mar;8(1):347-359. doi: 10.1007/s40744-020-00274-9. Epub 2021 Jan 9. PMID: 33420967; PMCID:

PMC7991020.


7: Lee TH, Koo BS, Nam B, Oh JS, Park SY, Lee S, Joo KB, Kim TH. Conventional disease-modifying antirheumatic drugs therapy may not slow spinal radiographic progression in ankylosing spondylitis: results from an 18-year longitudinal dataset. Ther Adv Musculoskelet Dis. 2020 Nov 28;12:1759720X20975912. doi: 10.1177/1759720X20975912. PMID: 33294039; PMCID: PMC7705797.


8: Koo BS, Jeong HJ, Son CN, Kim SH, Kim HJ, Kim GH, Jun JB. Distribution of serum uric acid levels and prence of hyper- and hypouricemia in a Korean

general population of 172,970. Korean J Intern Med. 2021 Mar;36(Suppl 1):S264-S272. doi: 10.3904/kjim.2020.116. Epub 2020 Nov 24. PMID: 33227843;

PMCID: PMC8009145.


9: Koo BS, Oh JS, Park SY, Shin JH, Ahn GY, Lee S, Joo KB, Kim TH. Response to 'Correspondence on "Tumour necrosis factor inhibitors slow radiographic

progression in patients with ankylosing spondylitis: 18-year real-world evidence" by Zhang et al. Ann Rheum Dis. 2020 Oct 1:annrheumdis-2020-218944. doi: 10.1136/annrheumdis-2020-218944. Epub ahead of print. PMID: 33004327.


10: Koo BS, Oh JS, Park SY, Shin JH, Ahn GY, Lee S, Joo KB, Kim TH. Tumour necrosis factor inhibitors slow radiographic progression in patients with

ankylosing spondylitis: 18-year real-world evidence. Ann Rheum Dis. 2020 Oct;79(10):1327-1332. doi: 10.1136/annrheumdis-2019-216741. Epub 2020 Jul 13.

PMID: 32660979.


11: Koo BS, Yoon BH. Characteristics of Appendicular Tissue Components in Patients with Rheumatoid Arthritis. J Bone Metab. 2020 Feb;27(1):35-42. doi:

10.11005/jbm.2020.27.1.35. Epub 2020 Feb 29. PMID: 32190607; PMCID: PMC7064364. 


12: Koo BS, Jo S, Kwon E, Shin JH, Hur JW, Kim TH. Effect of biologics in the level of cytokines in the synovial fluid of patients with ankylosing

spondylitis. Korean J Intern Med. 2020 Mar;35(2):465-473. doi: 10.3904/kjim.2018.364. Epub 2019 Dec 16. PMID: 31830775; PMCID: PMC7060997.


13: Koo BS, Song Y, Shin JH, Lee S, Kim TH. Evaluation of disease chronicity by bone marrow fat fraction using sacroiliac joint magnetic resonance imaging in patients with spondyloarthritis: A retrospective study. Int J Rheum Dis. 2019 Apr;22(4):734-741. doi: 10.1111/1756-185X.13485. Epub 2019 Feb 10. PMID:

30740910.


14: Koo BS, Song Y, Lee S, Sung YK, Shin KJ, Cho NH, Jun JB. Association of Asian mitochondrial DNA haplogroup B with new development of knee osteoarthritis in Koreans. Int J Rheum Dis. 2019 Mar;22(3):411-416. doi: 10.1111/1756-185X.13453. Epub 2018 Dec 13. PMID: 30549233.


15: Jo S, Koo BS, Lee B, Kwon E, Lee YL, Chung H, Sung IH, Park YS, Kim TH. A novel role for bone-derived cells in ankylosing spondylitis: Focus on IL-23.

Biochem Biophys Res Commun. 2017 Sep 23;491(3):787-793. doi: 10.1016/j.bbrc.2017.07.079. Epub 2017 Jul 18. PMID: 28728847.


16: Koo BS, Song Y, Lee S, Sung YK, Sung IH, Jun JB. Prence and distribution of sesamoid bones and accessory ossicles of the foot as determined by digital

tomosynthesis. Clin Anat. 2017 Nov;30(8):1072-1076. doi: 10.1002/ca.22952. Epub 2017 Jul 27. PMID: 28714106.


17: Koo BS, Song Y, Sung YK, Lee S, Jun JB. Prence and distribution of sesamoid bones in the hand determined using digital tomosynthesis. Clin Anat.

2017 Jul;30(5):608-613. doi: 10.1002/ca.22881. Epub 2017 Apr 19. PMID: 28340518.


18: Koo BS, Song Y, Joo KB, Lee S, Kim TH. Radiologic Changes in the Symphysis Pubis of Male Patients with Ankylosing Spondylitis. J Rheumatol. 2016

Feb;43(2):330-4. doi: 10.3899/jrheum.150711. Epub 2015 Dec 15. PMID: 26669926.


19: Lee DH, Melles RB, Joe SG, Lee JY, Kim JG, Lee CK, Yoo B, Koo BS, Kim JT, Marmor MF, Yoon YH. Pericentral hydroxychloroquine retinopathy in Korean

patients. Ophthalmology. 2015 Jun;122(6):1252-6. doi: 10.1016/j.ophtha.2015.01.014. Epub 2015 Feb 21. PMID: 25712474.


20: Koo BS, Hong S, Kim YJ, Kim YG, Lee CK, Yoo B. Mortality in patients with rheumatoid arthritis-associated interstitial lung disease treated with an anti-

tumor necrosis factor agent. Korean J Intern Med. 2015 Jan;30(1):104-9. doi: 10.3904/kjim.2015.30.1.104. Epub 2014 Dec 30. PMID: 25589842; PMCID: PMC4293548.


21: Koo BS, Hong S, Kim YJ, Kim YG, Lee CK, Yoo B. Lupus enteritis: clinical characteristics and predictive factors for recurrence. Lupus. 2015

May;24(6):628-32. doi: 10.1177/0961203314558858. Epub 2014 Nov 12. PMID: 25391541.


22: Koo BS, Koh YW, Hong S, Kim YJ, Kim YG, Lee CK, Yoo B. Clinicopathologic characteristics of IgG4-related retroperitoneal fibrosis among patients

initially diagnosed as having idiopathic retroperitoneal fibrosis. Mod Rheumatol. 2015 Mar;25(2):194-8. doi: 10.3109/14397595.2014.931908. Epub 2014

Jul 18. PMID: 25036229.


23: Kim YJ, Kim YG, Shim TS, Koo BS, Hong S, Lee CK, Yoo B. Safety of resuming tumour necrosis factor inhibitors in patients who developed tuberculosis as a complication of previous TNF inhibitors. Rheumatology (Oxford). 2014 Aug;53(8):1477-81. doi: 10.1093/rheumatology/keu041. Epub 2014 Mar 27. PMID:

24681840.


24: So MW, Koo BS, Kim YJ, Kim YG, Lee CK, Yoo B. Successful rituximab treatment of refractory hemophagocytic lymphohistiocytosis and autoimmune hemolytic anemia associated with systemic lupus erythematosus. Mod Rheumatol. 2014 Sep;24(5):855-7. doi: 10.3109/14397595.2013.874740. Epub 2014 Feb 11. PMID: 24517558.


25: Yoon DL, Kim YJ, Koo BS, Kim YG, Lee CK, Yoo B. Neuro-behcet's disease in South Korea: clinical characteristics and treatment response. Int J Rheum Dis.

2014 May;17(4):453-8. doi: 10.1111/1756-185X.12265. Epub 2014 Feb 8. PMID: 24506839.


26: Koo BS, Koh YW, Hong S, Kim YJ, Kim YG, Lee CK, Yoo B. Frequency of immunoglobulin G4-related aortitis in cases with aortic resection and their

clinical characteristics compared to other aortitises. Int J Rheum Dis. 2014 May;17(4):420-4. doi: 10.1111/1756-185X.12279. Epub 2014 Jan 22. PMID: 24447903.


27: Kim YJ, Koo BS, Kim YG, Lee CK, Yoo B. Clinical features and prognosis in 82 patients with adult- Still's disease. Clin Exp Rheumatol. 2014 Jan-

Feb;32(1):28-33. Epub 2013 Sep 18. PMID: 24050706.


28: So MW, Heo HM, Koo BS, Kim YG, Lee CK, Yoo B. Efficacy of incentive spirometer exercise on pulmonary functions of patients with ankylosing

spondylitis stabilized by tumor necrosis factor inhibitor therapy. J Rheumatol. 2012 Sep;39(9):1854-8. doi: 10.3899/jrheum.120137. Epub 2012 Aug 1. PMID:

22859343.


29: So MW, Lee EJ, Lee HS, Koo BS, Kim YG, Lee CK, Yoo B. Protective effects of ginsenoside Rg3 on human osteoarthritic chondrocytes. Mod Rheumatol. 2013 Jan;23(1):104-11. doi: 10.1007/s10165-012-0635-8. Epub 2012 Mar 28. PMID: 22454193.


30: Kim YG, So MW, Koo BS, Chang EJ, Song SJ, Lee CK, Yoo B. The influence of interleukin-32γ on osteoclastogenesis with a focus on fusion-related genes. J Clin Immunol. 2012 Feb;32(1):201-6. doi: 10.1007/s10875-011-9611-x. Epub 2011 Nov 9. PMID: 22068911.


31: So MW, Koo BS, Kim YG, Lee CK, Yoo B. Idiopathic inflammatory myopathy associated with malignancy: a retrospective cohort of 151 Korean patients with dermatomyositis and polymyositis. J Rheumatol. 2011 Nov;38(11):2432-5. doi: 10.3899/jrheum.110320. Epub 2011 Aug 15. PMID: 21844145.


32: So MW, Koo BS, Kim YG, Lee CK, Yoo B. Predictive value of remission status after 6?months induction therapy in patients with proliferative lupus nephritis: a retrospective analysis. Clin Rheumatol. 2011 Nov;30(11):1399-405. doi: 10.1007/s10067-011-1778-2. Epub 2011 May 20. PMID: 21594768.


33: Cho CJ, Kim YG, Lee SG, Lee CK, Kim JH, Koo BS, Yoo B. Inflammatory and noninflammatory vascular disease causing hemobilia. J Clin Rheumatol. 2011

Apr;17(3):138-41. doi: 10.1097/RHU.0b013e318214ef95. PMID: 21441818.