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구본산

구본산

류마티스내과

전문과목

류마티스관절염, 강직성척추염, 베체트병, 루푸스 / 통풍클리닉

진료시간

월, 화, 수, 목, 금, 토
오전
오후
학력사항

한양의대 졸업

울산의대 대학원 의학석사

울산의대 대학원 의학박사

서울아산병원 류마티스내과 임상강사 및 연구강사

한양대학교병원 류마티스내과 임상강사

건국대학교 충주병원 류마티스내과 임상조교수

서울백병원 류마티스내과 조교수

서울백병원 류마티스내과 부교수 재직중

연구분야 (강직성 척추염, 류마티스관절염, 통풍)

세부전문질환분야 (류마티스 관절염, 강직성 척추염, 통풍, 루푸스, 근염, 전신경화증, 혈관염, 베체트병)

경력사항

한양의대 졸업

울산의대 대학원 의학석사

울산의대 대학원 의학박사

서울아산병원 류마티스내과 임상강사 및 연구강사

한양대학교병원 류마티스내과 임상강사

건국대학교 충주병원 류마티스내과 임상조교수

서울백병원 류마티스내과 조교수

서울백병원 류마티스내과 부교수 재직중

연구분야 (강직성 척추염, 류마티스관절염, 통풍)

세부전문질환분야 (류마티스 관절염, 강직성 척추염, 통풍, 루푸스, 근염, 전신경화증, 혈관염, 베체트병)

주요활동

미국 류마티스학회 정회원

유럽 류마티스학회 정회원

대한 류마티스 학회 정회원

대한 류마티스학회 척추관절증연구회 회원

대한 내과 학회 정회원

논문/저서

1: Koo BS, Park KY, Lee HJ, Kim HJ, Ahn HS, Yim SY, Jun JB. Effect of combined

pulmonary fibrosis and emphysema on patients with connective tissue diseases and

systemic sclerosis: a systematic review and meta-analysis. Arthritis Res Ther.

2021 Apr 6;23(1):100. doi: 10.1186/s13075-021-02494-y. PMID: 33823923; PMCID:

PMC8022385.

2: Nam B, Koo BS, Nam SW, Shin JH, Song Y, Cho SK, Sung YK, Kim TH. Gender

differences in factors associated with low quality of life and depression in

Korean patients with ankylosing spondylitis. Qual Life Res. 2021 Mar 10. doi:

10.1007/s11136-021-02800-w. Epub ahead of print. PMID: 33689133.

3: Nam B, Koo BS, Lee TH, Shin JH, Kim JJ, Lee S, Joo KB, Kim TH. Low BASDAI

score alone is not a good predictor of anti-tumor necrosis factor treatment

efficacy in ankylosing spondylitis: a retrospective cohort study. BMC

Musculoskelet Disord. 2021 Feb 4;22(1):140. doi: 10.1186/s12891-020-03941-8.

PMID: 33541326; PMCID: PMC7860220.

4: Ha SY, Shim YB, Lee MY, Koo BS, Kim JH, Jeon JY, Yoo HJ, Kim YJ, Shin JY,

Park MH. Comparative Cost-Effectiveness of Tofacitinib With Continuing

Conventional Synthetic Disease-Modifying Anti-Rheumatic Drugs for Active

Rheumatoid Arthritis in South Korea. Rheumatol Ther. 2021 Mar;8(1):395-409. doi:

10.1007/s40744-021-00278-z. Epub 2021 Jan 26. PMID: 33496958; PMCID: PMC7991041.

5: Koo BS, Lim YC, Lee MY, Jeon JY, Yoo HJ, Oh IS, Shin JY, Kim TH. The risk

factors and incidence of major infectious diseases in patients with ankylosing

spondylitis receiving tumor necrosis factor inhibitors. Mod Rheumatol. 2021 Feb

15:1-14. doi: 10.1080/14397595.2021.1878985. Epub ahead of print. PMID:

33494621.

6: Koo BS, Lim YC, Lee MY, Jeon JY, Yoo HJ, Oh IS, Shin JY, Kim TH. Dose

Reduction of Tumor Necrosis Factor Inhibitor and its Effect on Medical Costs for

Patients with Ankylosing Spondylitis. Rheumatol Ther. 2021 Mar;8(1):347-359.

doi: 10.1007/s40744-020-00274-9. Epub 2021 Jan 9. PMID: 33420967; PMCID:

PMC7991020.

7: Lee TH, Koo BS, Nam B, Oh JS, Park SY, Lee S, Joo KB, Kim TH. Conventional

disease-modifying antirheumatic drugs therapy may not slow spinal radiographic

progression in ankylosing spondylitis: results from an 18-year longitudinal

dataset. Ther Adv Musculoskelet Dis. 2020 Nov 28;12:1759720X20975912. doi:

10.1177/1759720X20975912. PMID: 33294039; PMCID: PMC7705797.

8: Koo BS, Jeong HJ, Son CN, Kim SH, Kim HJ, Kim GH, Jun JB. Distribution of

serum uric acid levels and prence of hyper- and hypouricemia in a Korean

general population of 172,970. Korean J Intern Med. 2021 Mar;36(Suppl

1):S264-S272. doi: 10.3904/kjim.2020.116. Epub 2020 Nov 24. PMID: 33227843;

PMCID: PMC8009145.

9: Koo BS, Oh JS, Park SY, Shin JH, Ahn GY, Lee S, Joo KB, Kim TH. Response to

'Correspondence on "Tumour necrosis factor inhibitors slow radiographic

progression in patients with ankylosing spondylitis: 18-year real-world

evidence" by Zhang et al. Ann Rheum Dis. 2020 Oct

1:annrheumdis-2020-218944. doi: 10.1136/annrheumdis-2020-218944. Epub ahead of

print. PMID: 33004327.

10: Koo BS, Oh JS, Park SY, Shin JH, Ahn GY, Lee S, Joo KB, Kim TH. Tumour

necrosis factor inhibitors slow radiographic progression in patients with

ankylosing spondylitis: 18-year real-world evidence. Ann Rheum Dis. 2020

Oct;79(10):1327-1332. doi: 10.1136/annrheumdis-2019-216741. Epub 2020 Jul 13.

PMID: 32660979.

11: Koo BS, Yoon BH. Characteristics of Appendicular Tissue Components in

Patients with Rheumatoid Arthritis. J Bone Metab. 2020 Feb;27(1):35-42. doi:

10.11005/jbm.2020.27.1.35. Epub 2020 Feb 29. PMID: 32190607; PMCID: PMC7064364.

12: Koo BS, Jo S, Kwon E, Shin JH, Hur JW, Kim TH. Effect of biologics in the

level of cytokines in the synovial fluid of patients with ankylosing

spondylitis. Korean J Intern Med. 2020 Mar;35(2):465-473. doi:

10.3904/kjim.2018.364. Epub 2019 Dec 16. PMID: 31830775; PMCID: PMC7060997.

13: Koo BS, Song Y, Shin JH, Lee S, Kim TH. Evaluation of disease chronicity by

bone marrow fat fraction using sacroiliac joint magnetic resonance imaging in

patients with spondyloarthritis: A retrospective study. Int J Rheum Dis. 2019

Apr;22(4):734-741. doi: 10.1111/1756-185X.13485. Epub 2019 Feb 10. PMID:

30740910.

14: Koo BS, Song Y, Lee S, Sung YK, Shin KJ, Cho NH, Jun JB. Association of

Asian mitochondrial DNA haplogroup B with new development of knee osteoarthritis

in Koreans. Int J Rheum Dis. 2019 Mar;22(3):411-416. doi:

10.1111/1756-185X.13453. Epub 2018 Dec 13. PMID: 30549233.

15: Jo S, Koo BS, Lee B, Kwon E, Lee YL, Chung H, Sung IH, Park YS, Kim TH. A

novel role for bone-derived cells in ankylosing spondylitis: Focus on IL-23.

Biochem Biophys Res Commun. 2017 Sep 23;491(3):787-793. doi:

10.1016/j.bbrc.2017.07.079. Epub 2017 Jul 18. PMID: 28728847.

16: Koo BS, Song Y, Lee S, Sung YK, Sung IH, Jun JB. Prence and distribution

of sesamoid bones and accessory ossicles of the foot as determined by digital

tomosynthesis. Clin Anat. 2017 Nov;30(8):1072-1076. doi: 10.1002/ca.22952. Epub

2017 Jul 27. PMID: 28714106.

17: Koo BS, Song Y, Sung YK, Lee S, Jun JB. Prence and distribution of

sesamoid bones in the hand determined using digital tomosynthesis. Clin Anat.

2017 Jul;30(5):608-613. doi: 10.1002/ca.22881. Epub 2017 Apr 19. PMID: 28340518.

18: Koo BS, Song Y, Joo KB, Lee S, Kim TH. Radiologic Changes in the Symphysis

Pubis of Male Patients with Ankylosing Spondylitis. J Rheumatol. 2016

Feb;43(2):330-4. doi: 10.3899/jrheum.150711. Epub 2015 Dec 15. PMID: 26669926.

19: Lee DH, Melles RB, Joe SG, Lee JY, Kim JG, Lee CK, Yoo B, Koo BS, Kim JT,

Marmor MF, Yoon YH. Pericentral hydroxychloroquine retinopathy in Korean

patients. Ophthalmology. 2015 Jun;122(6):1252-6. doi:

10.1016/j.ophtha.2015.01.014. Epub 2015 Feb 21. PMID: 25712474.

20: Koo BS, Hong S, Kim YJ, Kim YG, Lee CK, Yoo B. Mortality in patients with

rheumatoid arthritis-associated interstitial lung disease treated with an anti-

tumor necrosis factor agent. Korean J Intern Med. 2015 Jan;30(1):104-9. doi:

10.3904/kjim.2015.30.1.104. Epub 2014 Dec 30. PMID: 25589842; PMCID: PMC4293548.

21: Koo BS, Hong S, Kim YJ, Kim YG, Lee CK, Yoo B. Lupus enteritis: clinical

characteristics and predictive factors for recurrence. Lupus. 2015

May;24(6):628-32. doi: 10.1177/0961203314558858. Epub 2014 Nov 12. PMID:

25391541.

22: Koo BS, Koh YW, Hong S, Kim YJ, Kim YG, Lee CK, Yoo B. Clinicopathologic

characteristics of IgG4-related retroperitoneal fibrosis among patients

initially diagnosed as having idiopathic retroperitoneal fibrosis. Mod

Rheumatol. 2015 Mar;25(2):194-8. doi: 10.3109/14397595.2014.931908. Epub 2014

Jul 18. PMID: 25036229.

23: Kim YJ, Kim YG, Shim TS, Koo BS, Hong S, Lee CK, Yoo B. Safety of resuming

tumour necrosis factor inhibitors in patients who developed tuberculosis as a

complication of previous TNF inhibitors. Rheumatology (Oxford). 2014

Aug;53(8):1477-81. doi: 10.1093/rheumatology/keu041. Epub 2014 Mar 27. PMID:

24681840.

24: So MW, Koo BS, Kim YJ, Kim YG, Lee CK, Yoo B. Successful rituximab treatment

of refractory hemophagocytic lymphohistiocytosis and autoimmune hemolytic anemia

associated with systemic lupus erythematosus. Mod Rheumatol. 2014

Sep;24(5):855-7. doi: 10.3109/14397595.2013.874740. Epub 2014 Feb 11. PMID:

24517558.

25: Yoon DL, Kim YJ, Koo BS, Kim YG, Lee CK, Yoo B. Neuro-behcet's disease in

South Korea: clinical characteristics and treatment response. Int J Rheum Dis.

2014 May;17(4):453-8. doi: 10.1111/1756-185X.12265. Epub 2014 Feb 8. PMID:

24506839.

26: Koo BS, Koh YW, Hong S, Kim YJ, Kim YG, Lee CK, Yoo B. Frequency of

immunoglobulin G4-related aortitis in cases with aortic resection and their

clinical characteristics compared to other aortitises. Int J Rheum Dis. 2014

May;17(4):420-4. doi: 10.1111/1756-185X.12279. Epub 2014 Jan 22. PMID: 24447903.

27: Kim YJ, Koo BS, Kim YG, Lee CK, Yoo B. Clinical features and prognosis in 82

patients with adult- Still's disease. Clin Exp Rheumatol. 2014 Jan-

Feb;32(1):28-33. Epub 2013 Sep 18. PMID: 24050706.

28: So MW, Heo HM, Koo BS, Kim YG, Lee CK, Yoo B. Efficacy of incentive

spirometer exercise on pulmonary functions of patients with ankylosing

spondylitis stabilized by tumor necrosis factor inhibitor therapy. J Rheumatol.

2012 Sep;39(9):1854-8. doi: 10.3899/jrheum.120137. Epub 2012 Aug 1. PMID:

22859343.

29: So MW, Lee EJ, Lee HS, Koo BS, Kim YG, Lee CK, Yoo B. Protective effects of

ginsenoside Rg3 on human osteoarthritic chondrocytes. Mod Rheumatol. 2013

Jan;23(1):104-11. doi: 10.1007/s10165-012-0635-8. Epub 2012 Mar 28. PMID:

22454193.

30: Kim YG, So MW, Koo BS, Chang EJ, Song SJ, Lee CK, Yoo B. The influence of

interleukin-32γ on osteoclastogenesis with a focus on fusion-related genes. J

Clin Immunol. 2012 Feb;32(1):201-6. doi: 10.1007/s10875-011-9611-x. Epub 2011

Nov 9. PMID: 22068911.

31: So MW, Koo BS, Kim YG, Lee CK, Yoo B. Idiopathic inflammatory myopathy

associated with malignancy: a retrospective cohort of 151 Korean patients with

dermatomyositis and polymyositis. J Rheumatol. 2011 Nov;38(11):2432-5. doi:

10.3899/jrheum.110320. Epub 2011 Aug 15. PMID: 21844145.

32: So MW, Koo BS, Kim YG, Lee CK, Yoo B. Predictive value of remission status

after 6?months induction therapy in patients with proliferative lupus nephritis:

a retrospective analysis. Clin Rheumatol. 2011 Nov;30(11):1399-405. doi:

10.1007/s10067-011-1778-2. Epub 2011 May 20. PMID: 21594768.

33: Cho CJ, Kim YG, Lee SG, Lee CK, Kim JH, Koo BS, Yoo B. Inflammatory and

noninflammatory vascular disease causing hemobilia. J Clin Rheumatol. 2011

Apr;17(3):138-41. doi: 10.1097/RHU.0b013e318214ef95. PMID: 21441818.