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원종철

Jong Chul Won

Department of Endocrinology

Specialty

Diabetes, metabolism

Treatment hours

Mon, Tue, Wed, Thur, Fri, Sat
Mon Tue Wed Thu Fri Sat
Education

Education and Training

M.D. Chonbuk National University Medical School, Korea

M.S. Internal Medicine, Postgraduate School, Ulsan University, Korea

Ph.D. Internal Medicine, Postgraduate School, Ulsan University, Korea


Career

Professional Experiences

Internship Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

1998 ? 2002 Residency, Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

2002 ? 2005 Researcher, Korean Health Industry Development Institute

2005 ? 2006 Fellowship, Endocrinology and Metabolism, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

Clinical Instructor, Endocrinology and Metabolism, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea

Assistant Professor, Department of Internal Medicine, Sanggye Paik Hospital, Inje University School of Medicine, Seoul, Korea

Associate Professor, Department of Internal Medicine, Sanggye Paik Hospital, Inje University School of Medicine, Seoul, Korea

Professor, Department of Internal Medicine, Sanggye Paik Hospital, Inje University School of Medicine, Seoul, Korea

Main Activities

diabetic atherosclerosis, mechanism of obesity

Research/Publication

Park SS, Jang SS, Ahn CH, Kim JH, Jung HS, Cho YM, Lee YA, Shin CH, Chae JH,Kim JH, Choi SH, Jang HC, Bae JC, Won JC, Kim SH, Kim JI, Kwak SH, Park KS.Identifying Pathogenic Variants of Monogenic Diabetes Using Targeted Panel Sequencing in an East Asian Population. J Clin Endocrinol Metab. 2019 Apr 12.pii: jc.2018-02397. doi: 10.1210/jc.2018-02397. [Epub ahead of print] PubMed

PMID: 30977832.

Won JC, Rhee EJ, Yoo HJ. Fifty Years of Compassionate Care and Harmonious Collaboration of the Korean Diabetes Association: The 50th Anniversary of Korean Diabetes Association. Diabetes Metab J. 2018 Dec;42(6):475-479. doi: 10.4093/dmj.2018.0231. PubMed PMID: 30565442; PubMed Central PMCID: PMC6300435.

Kim SH, On JW, Pyo H, Ko KS, Won JC, Yang J, Park MJ. Percentage fractions of urinary di(2-ethylhexyl) phthalate metabolites: Association with obesity and insulin resistance in Korean girls. PLoS One. 2018 Nov 27;13(11):e0208081. doi:10.1371/journal.pone.0208081. eCollection 2018. Erratum in: PLoS One. 2018 Dec 19;13(12):e0209724. PubMed PMID: 30481198; PubMed Central PMCID: PMC6258563.

Park JH, Won JC. Patterns of Nerve Conduction Abnormalities in Patients with Type 2 Diabetes Mellitus According to the Clinical Phenotype Determined by the Current Perception Threshold. Diabetes Metab J. 2018 Dec;42(6):519-528. doi:10.4093/dmj.2018.0068. Epub 2018 Oct 24. PubMed PMID: 30398037; PubMed Central PMCID: PMC6300437.

Won JC, Lee JH, Kim JH, Kang ES, Won KC, Kim DJ, Lee MK. Diabetes Fact Sheet in Korea, 2016: An Appraisal of Current status.Diabetes Metab J. 2018 Oct;42(5):415-424. doi: 10.4093/dmj.2018.0017. Epub 2018 Aug 9. PubMed PMID:30113146; PubMed Central PMCID: PMC6202557.

Kim JD, Park CY, Cha BY, Ahn KJ, Kim IJ, Park KS, Lee HW, Min KW, Won JC,Chung MY, Kim JT, Kang JG, Park SW. Comparison of Adherence to Glimepiride/Metformin Sustained Release Once-daily Versus Glimepiride/Metformin Immediate Release BID Fixed-combination Therapy Using the Medication Event Monitoring System in Patients With Type 2 Diabetes. Clin Ther. 2018 May;40(5):752-761.e2. doi: 10.1016/j.clinthera.2018.04.002. Epub 2018 May 3. PubMed PMID: 29729957.

Won JC, Im YJ, Lee JH, Kim CH, Kwon HS, Cha BY, Park TS. Clinical Phenotype of Diabetic Peripheral Neuropathy and Relation to Symptom Patterns: Cluster and Factor Analysis in Patients with Type 2 Diabetes in Korea. J Diabetes Res. 2017;2017:5751687. doi: 10.1155/2017/5751687. Epub 2017 Dec 13. PubMed PMID: 29387729; PubMed Central PMCID: PMC5745734.

Ko TH, Marquez JC, Kim HK, Jeong SH, Lee S, Youm JB, Song IS, Seo DY, Kim HJ, Won DN, Cho KI, Choi MG, Rhee BD, Ko KS, Kim N, Won JC, Han J. Resistance exercise improves cardiac function and mitochondrial efficiency in diabetic rat hearts. Pflugers Arch. 2018 Feb;470(2):263-275. doi: 10.1007/s00424-017-2076-x. Epub 2017 Oct 14. PubMed PMID: 29032504.

Ha JH, Lee S, Kim Y, Moon JI, Seo J, Jang JH, Cho EH, Kim JM, Rhee BD, Ko KS,Yoo SJ, Won JC. Kallmann syndrome with a Tyr113His PROKR2 mutation. Medicine (Baltimore). 2017 Sep;96(35):e7974. doi: 10.1097/MD.0000000000007974. PubMed PMID: 28858133; PubMed Central PMCID: PMC5585527.

Won JC, Park TS. Recent Advances in Diagnostic Strategies for Diabetic Peripheral Neuropathy. Endocrinol Metab (Seoul). 2016 Jun;31(2):230-8. doi:10.3803/EnM.2016.31.2.230. Epub 2016 May 27. Review. PubMed PMID: 27246283; PubMed Central PMCID: PMC4923406.

Won JC, Hong JW, Noh JH, Kim DJ. Association Between Age at Menarche and Risk Factors for Cardiovascular Diseases in Korean Women: The 2010 to 2013 Korea National Health and Nutrition Examination Survey. Medicine (Baltimore). 2016 May;95(18):e3580. doi: 10.1097/MD.0000000000003580. PubMed PMID: 27149485; PubMed Central PMCID: PMC4863802.

Kim JM, Lee HJ, Kim KO, Won JC, Ko KS, Rhee BD. Clinical Evaluation of OneTouch Diabetes Management Software System in Patients with Type 2 Diabetes Mellitus. Diabetes Metab J. 2016 Apr;40(2):129-39. doi: 10.4093/dmj.2016.40.2.129. PubMed PMID: 27126883; PubMed Central PMCID: PMC4853220.

Won JC, Hong JW, Noh JH, Kim DJ. Association Between Estimated 24-h Urinary Sodium Excretion and Metabolic Syndrome in Korean Adults: The 2009 to 2011 Korea National Health and Nutrition Examination Survey. Medicine (Baltimore). 2016 Apr;95(15):e3153. doi: 10.1097/MD.0000000000003153. PubMed PMID: 27082553; PubMed Central PMCID: PMC4839797.

Kim TN, Lee EJ, Hong JW, Kim JM, Won JC, Kim MK, Noh JH, Ko KS, Rhee BD, Kim DJ. Relationship Between Sarcopenia and Albuminuria: The 2011 Korea National Health and Nutrition Examination Survey. Medicine (Baltimore). 2016 Jan;95(3):e2500. doi: 10.1097/MD.0000000000002500. PubMed PMID: 26817888; PubMed Central PMCID: PMC4998262.

Kim JM, Hong JW, Won JC, Noh JH, Ko KS, Rhee BD, Kim DJ. Glycated Hemoglobin Value for Fasting Plasma Glucose of 126 mg/dL in Korean: The 2011 Korea National Health and Nutrition Examination Survey. Diabetes Metab J. 2014 Dec;38(6):480-3. doi: 10.4093/dmj.2014.38.6.480. Epub 2014 Dec 15. PubMed PMID: 25541612; PubMed Central PMCID: PMC4273035.

16: Won JC, Hong JW, Kim JM, Kim TN, Noh JH, Ko KS, Rhee BD, Kim DJ. Increased prence of albuminuria in individuals with higher range of impaired fasting glucose: the 2011 Korea National Health and Nutrition Examination Survey. J Diabetes Complications. 2015 Jan-Feb;29(1):50-4. doi: 10.1016/j.jdiacomp.2014.08.006. Epub 2014 Aug 27. PubMed PMID: 25240717.

17: Won JC, Park CY, Oh SW, Lee ES, Youn BS, Kim MS. Plasma clusterin (ApoJ) levels are associated with adiposity and systemic inflammation. PLoS One. 2014 Jul 30;9(7):e103351. doi: 10.1371/journal.pone.0103351. eCollection 2014. PubMed PMID: 25076422; PubMed Central PMCID: PMC4116172.

18: Jeon JY, Kim DJ, Ko SH, Kwon HS, Lim S, Choi SH, Kim CS, An JH, Kim NH, Won JC, Kim JH, Cha BY, Song KH; Taskforce Team of Diabetes Fact Sheet of the Korean Diabetes Association. Current status of glycemic control of patients with diabetes in Korea: the fifth Korea national health and nutrition examination survey. Diabetes Metab J. 2014 Jun;38(3):197-203. doi: 10.4093/dmj.2014.38.3.197.Epub 2014 Jun 17. PubMed PMID: 25003073; PubMed Central PMCID: PMC4083026.

19: Kim TN, Park MS, Kim YJ, Lee EJ, Kim MK, Kim JM, Ko KS, Rhee BD, Won JC. Association of low muscle mass and combined low muscle mass and visceral obesity with low cardiorespiratory fitness. PLoS One. 2014 Jun 17;9(6):e100118. doi:

10.1371/journal.pone.0100118. eCollection 2014. PubMed PMID: 24937121; PubMed Central PMCID: PMC4061126

Prence and determinants of diabetic nephropathy in Korea: Korea national health and nutrition examination survey. Ahn JH, Yu JH, Ko SH, Kwon HS, Kim DJ, Kim JH, Kim CS, Song KH, Won JC, Lim S, Choi SH, Han K, Cha BY, Kim NH; Taskforce Team of Diabetes Fact Sheet of the Korean Diabetes Association. Diabetes Metab J. 2014 Apr;38(2):109-19. doi: 10.4093/dmj.2014.38.2.109. Epub 2014 Apr 18.

Validity of the medical outcomes study sleep scale in patients with painful diabetic peripheral neuropathy in Korea. Kim SS, Won JC, Kwon HS, Kim CH, Lee JH, Park TS, Ko KS, Cha BY.J Diabetes Investig. 2013 Jul 8;4(4):405-9. doi: 10.1111/jdi.12066. Epub 2013 Mar 21.

Prence of and Factors Associated with Lens Opacities in a Korean Adult Population with and without Diabetes: The 2008-2009 Korea National Health and Nutrition Examination Survey. Kim TN, Lee JE, Lee EJ, Won JC, Noh JH, Ko KS, Rhee BD, Kim DJ. PLoS One. 2014 Apr 9;9(4):e94189. doi: 10.1371/journal.pone.0094189. eCollection 2014.

Higher prence and awareness, but lower control rate of hypertension in patients with diabetes than general population: the fifth korean national health and nutrition examination survey in 2011. Ko SH, Kwon HS, Kim DJ, Kim JH, Kim NH, Kim CS, Song KH, Won JC, Lim S, Choi SH, Han K, Park YM, Cha BY; Taskforce Team of Diabetes Fact Sheet of the Korean Diabetes Association. Diabetes Metab J. 2014 Feb;38(1):51-7. doi: 10.4093/dmj.2014.38.1.51. Epub 2014 Feb 19.

Prence, awareness, and management of obesity in Korea: data from the Korea national health and nutrition examination survey (1998-2011). Kim CS, Ko SH, Kwon HS, Kim NH, Kim JH, Lim S, Choi SH, Song KH, Won JC, Kim DJ, Cha BY; Taskforce Team of Diabetes Fact Sheet of the Korean Diabetes Association. Diabetes Metab J. 2014 Feb;38(1):35-43. doi: 10.4093/dmj.2014.38.1.35. Epub 2014 Feb 19.

Current Status of Diabetic Peripheral Neuropathy in Korea: Report of a Hospital-Based Study of Type 2 Diabetic Patients in Korea by the Diabetic Neuropathy Study Group of the Korean Diabetes Association. Won JC, Kim SS, Ko KS, Cha BY. Diabetes Metab J. 2014 Feb;38(1):25-31. Review.

Prence and clinical implications of painful diabetic peripheral neuropathy in type 2 diabetes: results from a nationwide hospital-based study of diabetic neuropathy in Korea. Kim SS, Won JC, Kwon HS, Kim CH, Lee JH, Park TS, Ko KS, Cha BY. Diabetes Res Clin Pract. 2014 Mar;103(3):522-9.

Prence and Management of Dyslipidemia in Korea: Korea National Health and Nutrition Examination Survey during 1998 to 2010. Roh E, Ko SH, Kwon HS, Kim NH, Kim JH, Kim CS, Song KH, Won JC, Kim DJ, Choi SH, Lim S, Cha BY; Taskforce Team of Diabetes Fact Sheet of the Korean Diabetes Association. Diabetes Metab J. 2013 Dec;37(6):433-49.

Prence of and factors associated with albuminuria in the Korean adult population: the 2011 Korea National Health and Nutrition Examination Survey. Won JC, Lee YJ, Kim JM, Han SY, Noh JH, Ko KS, Rhee BD, Kim DJ. PLoS One. 2013 Dec 27;8(12):e83273.

Prence of Diabetes and Prediabetes according to Fasting Plasma Glucose and HbA1c. Jeon JY, Ko SH, Kwon HS, Kim NH, Kim JH, Kim CS, Song KH, Won JC, Lim S, Choi SH, Jang MJ, Kim Y, Oh K, Kim DJ, Cha BY; Taskforce Team of Diabetes Fact Sheet of the Korean Diabetes Association. Diabetes Metab J. 2013 Oct;37(5):349-57.

Association between serum vaspin level and metabolic syndrome in healthy Korean subjects. Kim JM, Kim TN, Won JC. Metab Syndr Relat Disord. 2013 Dec;11(6):385-91.

Serum adipocyte fatty acid-binding protein levels are independently associated with sarcopenic obesity. Kim TN, Won JC, Kim YJ, Lee EJ, Kim MK, Park MS, Lee SK, Kim JM, Ko KS, Rhee BD. Diabetes Res Clin Pract. 2013 Aug;101(2):210-7.

Increased plasma levels of retinol-binding protein 4 with visceral obesity is associated with cardiovascular risk factors. Won JC, Park CY, Oh SW, Park SW. J Diabetes Investig. 2012 Oct 18;3(5):457-63.

Prence and clinical characteristics of diabetic peripheral neuropathy in hospital patients with Type 2 diabetes in Korea. Won JC, Kwon HS, Kim CH, Lee JH, Park TS, Ko KS, Cha BY. Diabet Med. 2012 Sep;29(9):e290-6.

A decision tree-based approach for identifying urban-rural differences in metabolic syndrome risk factors in the adult Korean population. Kim TN, Kim JM, Won JC, Park MS, Lee SK, Yoon SH, Kim HR, Ko KS, Rhee BD. J Endocrinol Invest. 2012 Oct;35(9):847-52.

Type 2 diabetes in urban and rural districts in Korea: factors associated with prence difference. Lee HY, Won JC, Kang YJ, Yoon SH, Choi EO, Bae JY, Sung MH, Kim HR, Yang JH, Oh J, Lee YM, Park NH, Ko KS, Rhee BD. J Korean Med Sci. 2010 Dec;25(12):1777-83. doi: 10.3346/jkms.2010.25.12.1777. Epub 2010 Nov 24.

Alpha-lipoic acid activates dimethylarginine dimethylaminohydrolase in cultured endothelial cells. Lee WJ, Kim SW, Kim GH, Han SM, Won JC, Jung CH, Park HS, Choi do S, Lee KU, Park JY. Biochem Biophys Res Commun. 2010 Aug 6;398(4):653-8. doi: 10.1016/j.bbrc.2010.06.127. Epub 2010 Jul 11. Erratum in: Biochem Biophys Res Commun. 2010 Oct 22;401(3):491.

Peroxisome proliferator-activated receptor-gamma coactivator 1-alpha overexpression prevents endothelial apoptosis by increasing ATP/ADP translocase activity. Won JC, Park JY, Kim YM, Koh EH, Seol S, Jeon BH, Han J, Kim JR, Park TS, Choi CS, Lee WJ, Kim MS, Lee IK, Youn JH, Lee KU. Arterioscler Thromb Vasc Biol. 2010 Feb;30(2):290-7. doi: 10.1161/ATVBAHA.109.198721.

Mechanisms of adipose tissue redistribution with rosiglitazone treatment in various adipose depots. Kang JG, Park CY, Ihm SH, Yoo HJ, Park H, Rhee EJ, Won JC, Lee WY, Oh KW, Park SW, Kim SW. Metabolism. 2010 Jan;59(1):46-53. doi: 10.1016/j.metabol.2009.07.004.

Association of plasma levels of resistin with subcutaneous fat mass and markers of inflammation but not with metabolic determinants or insulin resistance. Won JC, Park CY, Lee WY, Lee ES, Oh SW, Park SW. J Korean Med Sci. 2009 Aug;24(4):695-700.

Central administration of an endoplasmic reticulum stress inducer inhibits the anorexigenic effects of leptin and insulin. Won JC, Jang PG, Namkoong C, Koh EH, Kim SK, Park JY, Lee KU, Kim MS. Obesity (Silver Spring). 2009 Oct;17(10):1861-5.

Glucose-responsive gene expression system for gene therapy. Won JC, Rhee BD, Ko KS. Adv Drug Deliv Rev. 2009 Jul 2;61(7-8):633-40.

Serum gamma-glutamyl transferase activity predicts future development of metabolic syndrome defined by 2 different criteria. Jo SK, Lee WY, Rhee EJ, Won JC, Jung CH, Park CY, Oh KW, Park SW, Kim SW. Clin Chim Acta. 2009 May;403(1-2):234-40.

1,5-Anhydroglucitol reflects postprandial hyperglycemia and a decreased insulinogenic index, even in subjects with prediabetes and well-controlled type 2 diabetes. Won JC, Park CY, Park HS, Kim JH, Choi ES, Rhee EJ, Lee WY, Oh KW, Kim SW, Park SW. Diabetes Res Clin Pract. 2009 Apr;84(1):51-7.

Relationship between body composition and bone mineral density (BMD) in perimenopausal Korean women. Kim CJ, Oh KW, Rhee EJ, Kim KH, Jo SK, Jung CH, Won JC, Park CY, Lee WY, Park SW, Kim SW. Clin Endocrinol (Oxf). 2009 Jul;71(1):18-26.

Higher serum free thyroxine levels are associated with coronary artery disease. Jung CH, Rhee EJ, Shin HS, Jo SK, Won JC, Park CY, Kim BJ, Sung KC, Kim BS, Lee WY, Oh KW, Kang JH, Park SW, Lee MH, Kim SW. Endocr J. 2008 Oct;55(5):819-26.

Clinical and genetic analysis of a Korean patient with late- X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism: identification of a novel mutation in the NR0B1 gene. Lee YW, Won JC, Ki CS, Lee HY, Ahn HS, Lee YK, Kim YH, Kim CH. J Int Med Res. 2008 Mar-Apr;36(2):357-61.

Role of hypothalamic Foxo1 in the regulation of food intake and energy homeostasis. Kim MS, Pak YK, Jang PG, Namkoong C, Choi YS, Won JC, Kim KS, Kim SW, Kim HS, Park JY, Kim YB, Lee KU. Nat Neurosci. 2006 Jul;9(7):901-6.

AMPK activation increases fatty acid oxidation in skeletal muscle by activating PPARalpha and PGC-1. Lee WJ, Kim M, Park HS, Kim HS, Jeon MJ, Oh KS, Koh EH, Won JC, Kim MS, Oh GT, Yoon M, Lee KU, Park JY. Biochem Biophys Res Commun. 2006 Feb 3;340(1):291-5.

Alpha-lipoic acid prevents endothelial dysfunction in obese rats via activation of AMP-activated protein kinase. Lee WJ, Lee IK, Kim HS, Kim YM, Koh EH, Won JC, Han SM, Kim MS, Jo I, Oh GT, Park IS, Youn JH, Park SW, Lee KU, Park JY. Arterioscler Thromb Vasc Biol. 2005 Dec;25(12):2488-94.

Obesity: the role of hypothalamic AMP-activated protein kinase in body weight regulation. Lee WJ, Koh EH, Won JC, Kim MS, Park JY, Lee KU. Int J Biochem Cell Biol. 2005 Nov;37(11):2254-9.

Alpha-lipoic acid increases insulin sensitivity by activating AMPK in skeletal muscle. Lee WJ, Song KH, Koh EH, Won JC, Kim HS, Park HS, Kim MS, Kim SW, Lee KU, Park JY. Biochem Biophys Res Commun. 2005 Jul 8;332(3):885-91.